Top Depression Treatment Centers in Missouri
In 2023, the Behavioral Risk Factor Surveillance System documented that 23.1% of Missouri adults had been previously told by a health professional that they had some form of depression, exceeding the national average of 19%. High firearm-suicide rates, rural hospital closures that limit access and repeated flooding and destructive tornadoes that disrupt livelihoods can add to the pressures individuals statewide might experience and exacerbate mood disorders. These realities make evidence-driven support critical from Kansas City to the Bootheel.
10 Top Reviewed Depression Centers in Missouri
PsyWeb reviewed depression centers in Missouri to feature top facilities that were licensed, nationally accredited providers. These facilities offer everything from dedicated depression units in hospitals of larger cities to residential programs serving multiple rural counties. Hospitals, community mental health organizations and private retreats may offer cognitive therapies, medication oversight and peer support, then coordinate follow-ups with outpatient clinics to help you sustain long-term mental wellness.
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Missouri Treatment Centers
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1. Compass Health
805 North Orange Street, Butler, MO 64730
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Compass Health
Phone: 660-442-1054
Intake: 888-403-1071
Facility Type: Mental Health
Facility Specialization: Outpatient mental health facility
Facility Operation: Private non-profit organization
Licence / Certification / Acreditation: Federally Qualified Health Center
Age Groups Accepted: Children/Adolescents, Young Adults, Adults, Seniors
Facility Details
Type of Care
- Substance use treatment
- Mental health treatment
- Treatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Payment & Insurance Accepted
- County or local government funds
- Community Mental Health Block Grants
- Community Service Block Grants
- Medicare
- Medicaid
- Federal military insurance (e.g., TRICARE)
- Other State funds
- Private health insurance
- Cash or self-payment
- State-financed health insurance plan other than Medicaid
- State mental health agency (or equivalent) funds
Payment Assistance Available
- Sliding fee scale (fee is based on income and other factors)
Facility Services
Treatment & Recovery
- Mentoring/peer support
Assessment / Pre-Treatment
- Screening for tobacco use
Special Programs / Groups Offered
- Clients with co-occurring mental and substance use disorders
Emergency Health Services
- Crisis intervention team
Education and Counseling Services
- Smoking/vaping/tobacco cessation counseling
Additional Services
Language Services
- Sign language services for the deaf and hard of hearing
Additional Services
- Assertive community treatment
- Family psychoeducation
- Psychosocial rehabilitation services
- Supported employment
- Case management service
- Integrated primary care services
- Suicide prevention services
Smoking & Vaping Policy
- Smoking not permitted
- Vaping not permitted
Treatment Details
Pharmacotherapies
- Chlorpromazine
- Droperidol
- Fluphenazine
- Haloperidol
- Loxapine
- Aripiprazole
- Asenapine
- Brexpiprazole
- Cariprazine
- Clozapine
- IIoperidone
- Lurasidone
- Olanzapine
- Olanzapine/Fluoxetine combination
- Paliperidone
- Quetiapine
- Risperidone
- Ziprasidone
- Nicotine replacement
- Non-nicotine smoking/tobacco cessation
- Antipsychotics used in treatment of SMI
2. Arthur Center Behavioral Health
581 Commons Drive, Fulton, MO 65251
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Arthur Center Behavioral Health
Phone: 573-582-1234 x3011
Intake: 573-582-1234
Facility Type: Mental Health
Facility Specialization: Certified Community Behavioral Health Clinic
Facility Operation: Private non-profit organization
Licence / Certification / Acreditation: Federally Qualified Health Center
Age Groups Accepted: Children/Adolescents, Young Adults, Adults, Seniors
Facility Details
Type of Care
- Substance use treatment
- Mental health treatment
Payment & Insurance Accepted
- Community Mental Health Block Grants
- Medicare
- Medicaid
- Federal military insurance (e.g., TRICARE)
- Private health insurance
- State corrections or juvenile justice funds
- Cash or self-payment
- State mental health agency (or equivalent) funds
- State welfare or child and family services funds
- U.S. Department of VA funds
Payment Assistance Available
- Payment assistance (check with facility for details)
- Sliding fee scale (fee is based on income and other factors)
Facility Services
Treatment & Recovery
- Housing services
Assessment / Pre-Treatment
- Screening for tobacco use
Special Programs / Groups Offered
- Criminal justice (other than DUI/DWI)/Forensic clients
Emergency Health Services
- Crisis intervention team
- Psychiatric emergency onsite services
- Psychiatric emergency mobile/off-site services
- Psychiatric emergency walk-in services
Education and Counseling Services
- Smoking/vaping/tobacco cessation counseling
Additional Services
Language Services
- Sign language services for the deaf and hard of hearing
Additional Services
- Chronic disease/illness management
- Court-ordered outpatient treatment
- Diet and exercise counseling
- Family psychoeducation
- Intensive case management
- Illness management and recovery
- Supported housing
- Case management service
- Suicide prevention services
Smoking & Vaping Policy
- Smoking not permitted
- Vaping not permitted
Treatment Details
Pharmacotherapies
- Haloperidol
- Aripiprazole
- Asenapine
- Brexpiprazole
- Cariprazine
- Clozapine
- IIoperidone
- Lurasidone
- Olanzapine
- Paliperidone
- Quetiapine
- Risperidone
- Ziprasidone
- Nicotine replacement
- Non-nicotine smoking/tobacco cessation
- Antipsychotics used in treatment of SMI
3. HCC Network
206 N Bismark St, Concordia, MO 64020
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HCC Network
Phone: 660-463-0234
Facility Type: Mental Health
Facility Operation: Private non-profit organization
Licence / Certification / Acreditation: Federally Qualified Health Center
Age Groups Accepted: Children/Adolescents, Young Adults, Adults, Seniors
Facility Details
Type of Care
- Substance use treatment
- Mental health treatment
- Treatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Payment & Insurance Accepted
- Medicare
- Medicaid
- Private health insurance
- Cash or self-payment
Payment Assistance Available
- Sliding fee scale (fee is based on income and other factors)
Facility Services
Treatment & Recovery
- Mentoring/peer support
Assessment / Pre-Treatment
- Screening for tobacco use
Education and Counseling Services
- Smoking/vaping/tobacco cessation counseling
Additional Services
Testing
- HIV testing
- STD testing
- TB screening
- Metabolic syndrome monitoring
- Testing for Hepatitis B (HBV)
- Testing for Hepatitis C (HCV)
Additional Services
- Chronic disease/illness management
- Diet and exercise counseling
- Case management service
- Integrated primary care services
Smoking & Vaping Policy
- Smoking not permitted
- Vaping not permitted
4. East Central MO Behavioral Health
340 Kelley Parkway, Mexico, MO 65265
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East Central MO Behavioral Health
Phone: 573-582-1234
Facility Type: Mental Health
Facility Specialization: Certified Community Behavioral Health Clinic
Facility Operation: Private non-profit organization
Licence / Certification / Acreditation: Federally Qualified Health Center
Age Groups Accepted: Children/Adolescents, Young Adults, Adults, Seniors
Facility Details
Type of Care
- Substance use treatment
- Mental health treatment
Payment & Insurance Accepted
- Community Mental Health Block Grants
- Medicare
- Medicaid
- Federal military insurance (e.g., TRICARE)
- Private health insurance
- State corrections or juvenile justice funds
- Cash or self-payment
- State mental health agency (or equivalent) funds
- U.S. Department of VA funds
Payment Assistance Available
- Payment assistance (check with facility for details)
- Sliding fee scale (fee is based on income and other factors)
Facility Services
Treatment & Recovery
- Housing services
- Mentoring/peer support
Assessment / Pre-Treatment
- Screening for tobacco use
Special Programs / Groups Offered
- Criminal justice (other than DUI/DWI)/Forensic clients
- Clients with co-occurring mental and substance use disorders
Emergency Health Services
- Crisis intervention team
- Psychiatric emergency onsite services
- Psychiatric emergency mobile/off-site services
- Psychiatric emergency walk-in services
Education and Counseling Services
- Smoking/vaping/tobacco cessation counseling
Additional Services
Testing
- HIV testing
- STD testing
- TB screening
- Metabolic syndrome monitoring
- Testing for Hepatitis B (HBV)
- Testing for Hepatitis C (HCV)
- Laboratory testing
Language Services
- Sign language services for the deaf and hard of hearing
- Other languages (excluding Spanish)
Additional Services
- Chronic disease/illness management
- Court-ordered outpatient treatment
- Diet and exercise counseling
- Family psychoeducation
- Intensive case management
- Illness management and recovery
- Case management service
- Integrated primary care services
- Suicide prevention services
Smoking & Vaping Policy
- Smoking not permitted
- Vaping not permitted
Treatment Details
Pharmacotherapies
- Haloperidol
- Aripiprazole
- Asenapine
- Brexpiprazole
- Cariprazine
- Clozapine
- IIoperidone
- Lurasidone
- Olanzapine
- Paliperidone
- Quetiapine
- Risperidone
- Ziprasidone
- Nicotine replacement
- Non-nicotine smoking/tobacco cessation
- Antipsychotics used in treatment of SMI
5. Harry S Truman Memorial
800 Hospital Drive, Columbia, MO 65201
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Harry S Truman Memorial
Phone: 573-814-6000 x53441
Intake: 573-814-6000 x53491
Facility Type: Mental Health
Facility Specialization: Veterans Affairs Medical Center or other VA healthcare facility
Facility Operation: U.S. Department of Veterans Affairs, Federal Government
Licence / Certification / Acreditation: Federally Qualified Health Center
Age Groups Accepted: Young Adults, Adults, Seniors
Facility Details
Type of Care
- Substance use treatment
- Mental health treatment
- Treatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Payment & Insurance Accepted
- Medicare
- Medicaid
- Federal military insurance (e.g., TRICARE)
- Private health insurance
- U.S. Department of VA funds
Facility Services
Treatment & Recovery
- Housing services
- Mentoring/peer support
Assessment / Pre-Treatment
- Screening for tobacco use
Special Programs / Groups Offered
- Seniors or older adults
- Veterans
- Criminal justice (other than DUI/DWI)/Forensic clients
- Clients with co-occurring mental and substance use disorders
- Clients who have experienced trauma
- Persons with post-traumatic stress disorder (PTSD)
- Persons 18 and older with serious mental illness (SMI)
Emergency Health Services
- Crisis intervention team
- Psychiatric emergency onsite services
- Psychiatric emergency walk-in services
Education and Counseling Services
- Smoking/vaping/tobacco cessation counseling
Additional Services
Testing
- HIV testing
- STD testing
- TB screening
- Metabolic syndrome monitoring
- Testing for Hepatitis B (HBV)
- Testing for Hepatitis C (HCV)
- Laboratory testing
Additional Services
- Chronic disease/illness management
- Court-ordered outpatient treatment
- Diet and exercise counseling
- Family psychoeducation
- Intensive case management
- Legal advocacy
- Psychosocial rehabilitation services
- Supported employment
- Supported housing
- Vocational rehabilitation services
- Case management service
- Integrated primary care services
- Suicide prevention services
Smoking & Vaping Policy
- Smoking not permitted
- Vaping not permitted
Treatment Details
Pharmacotherapies
- Chlorpromazine
- Fluphenazine
- Haloperidol
- Perphenazine
- Nicotine replacement
- Non-nicotine smoking/tobacco cessation
- Antipsychotics used in treatment of SMI
6. Brightli
1805 East Walnut Street, Columbia, MO 65201
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Brightli
Phone: 417-761-5000
Facility Type: Mental Health
Facility Specialization: Certified Community Behavioral Health Clinic
Facility Operation: Private non-profit organization
Licence / Certification / Acreditation: Federally Qualified Health Center
Age Groups Accepted: Children/Adolescents, Young Adults, Adults, Seniors
Facility Details
Type of Care
- Substance use treatment
- Mental health treatment
- Treatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Payment & Insurance Accepted
- Medicare
- Medicaid
- Federal military insurance (e.g., TRICARE)
- Private health insurance
- Cash or self-payment
- State mental health agency (or equivalent) funds
Payment Assistance Available
- Payment assistance (check with facility for details)
Facility Services
Treatment & Recovery
- Mentoring/peer support
Assessment / Pre-Treatment
- Screening for tobacco use
Special Programs / Groups Offered
- Young adults
- Clients with co-occurring mental and substance use disorders
Emergency Health Services
- Crisis intervention team
- Psychiatric emergency onsite services
- Psychiatric emergency mobile/off-site services
Education and Counseling Services
- Smoking/vaping/tobacco cessation counseling
Additional Services
Language Services
- Sign language services for the deaf and hard of hearing
Additional Services
- Assertive community treatment
- Psychosocial rehabilitation services
- Case management service
- Suicide prevention services
Smoking & Vaping Policy
- Smoking permitted in designated area
- Vaping permitted in designated area
Treatment Details
Pharmacotherapies
- Nicotine replacement
- Non-nicotine smoking/tobacco cessation
- Antipsychotics used in treatment of SMI
7. River Rock Behavioral Health
50 Crestwood Executive Center, Saint Louis, MO 63126
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River Rock Behavioral Health
Phone: 314-408-7676
Facility Type: Mental Health
Facility Operation: Private for-profit organization
Licence / Certification / Acreditation: Mental health clinic or mental health center
Age Groups Accepted: Children/Adolescents, Young Adults, Adults, Seniors
Facility Details
Type of Care
- Mental health treatment
Payment & Insurance Accepted
- Medicare
- Medicaid
- Federal military insurance (e.g., TRICARE)
- Private health insurance
- Cash or self-payment
Additional Services
Additional Services
- Family psychoeducation
- Suicide prevention services
Smoking & Vaping Policy
- Smoking not permitted
- Vaping not permitted
8. Swope Health Services
3801 Dr MLK Jr Boulevard, Kansas City, MO 64130
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Swope Health Services
Phone: 816-923-5800
Intake: 816-599-5856
Facility Type: Mental Health
Facility Specialization: Certified Community Behavioral Health Clinic
Facility Operation: Private non-profit organization
Licence / Certification / Acreditation: Federally Qualified Health Center
Age Groups Accepted: Children/Adolescents, Young Adults, Adults, Seniors
Facility Details
Type of Care
- Substance use treatment
- Mental health treatment
- Treatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Payment & Insurance Accepted
- County or local government funds
- Community Mental Health Block Grants
- Community Service Block Grants
- Federal Grants
- Medicare
- Medicaid
- Federal military insurance (e.g., TRICARE)
- Other State funds
- Private health insurance
- State corrections or juvenile justice funds
- Cash or self-payment
- State-financed health insurance plan other than Medicaid
- State mental health agency (or equivalent) funds
- State welfare or child and family services funds
Payment Assistance Available
- Payment assistance (check with facility for details)
Facility Services
Treatment & Recovery
- Housing services
- Mentoring/peer support
Assessment / Pre-Treatment
- Screening for tobacco use
Special Programs / Groups Offered
- Young adults
- Criminal justice (other than DUI/DWI)/Forensic clients
- Clients with co-occurring mental and substance use disorders
- Children/adolescents with serious emotional disturbance (SED)
- Persons 18 and older with serious mental illness (SMI)
Emergency Health Services
- Crisis intervention team
- Psychiatric emergency onsite services
- Psychiatric emergency mobile/off-site services
- Psychiatric emergency walk-in services
Education and Counseling Services
- Smoking/vaping/tobacco cessation counseling
Additional Services
Testing
- Metabolic syndrome monitoring
- Laboratory testing
Language Services
- Sign language services for the deaf and hard of hearing
Additional Services
- Chronic disease/illness management
- Court-ordered outpatient treatment
- Diet and exercise counseling
- Family psychoeducation
- Intensive case management
- Illness management and recovery
- Psychosocial rehabilitation services
- Supported employment
- Supported housing
- Vocational rehabilitation services
- Case management service
- Integrated primary care services
- Suicide prevention services
- Education services
Smoking & Vaping Policy
- Smoking not permitted
- Vaping not permitted
Treatment Details
Pharmacotherapies
- Nicotine replacement
- Non-nicotine smoking/tobacco cessation
- Antipsychotics used in treatment of SMI
9. Centrec Care
1224 Fern Ridge Parkway, Saint Louis, MO 63141
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Centrec Care
Phone: 314-205-8068 x0
Intake: 314-205-8068 x200
Facility Type: Mental Health
Facility Specialization: Partial hospitalization/day treatment
Facility Operation: Private for-profit organization
Licence / Certification / Acreditation: Mental health clinic or mental health center
Age Groups Accepted: Young Adults, Adults, Seniors
Facility Details
Type of Care
- Substance use treatment
- Mental health treatment
Payment & Insurance Accepted
- Private health insurance
- Cash or self-payment
Facility Services
Treatment & Recovery
- Mentoring/peer support
Assessment / Pre-Treatment
- Screening for tobacco use
Special Programs / Groups Offered
- Criminal justice (other than DUI/DWI)/Forensic clients
- Clients with co-occurring mental and substance use disorders
- Clients with HIV or AIDS
- Clients who have experienced trauma
- Persons with post-traumatic stress disorder (PTSD)
Emergency Health Services
- Crisis intervention team
- Psychiatric emergency walk-in services
Additional Services
Additional Services
- Court-ordered outpatient treatment
- Diet and exercise counseling
- Family psychoeducation
- Intensive case management
- Case management service
- Integrated primary care services
- Suicide prevention services
- Education services
Smoking & Vaping Policy
- Smoking permitted in designated area
- Vaping permitted in designated area
Treatment Details
Pharmacotherapies
- Chlorpromazine
- Perphenazine
- Aripiprazole
- Brexpiprazole
- Cariprazine
- Clozapine
- Lurasidone
- Olanzapine
- Olanzapine/Fluoxetine combination
- Quetiapine
- Risperidone
- Ziprasidone
- Nicotine replacement
- Non-nicotine smoking/tobacco cessation
- Antipsychotics used in treatment of SMI
10. Betty Jean Kerr Peoples Health Centers
4236 Lindell Boulevard, Saint Louis, MO 63108
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Betty Jean Kerr Peoples Health Centers
Phone: 314-531-1770 x4010
Facility Type: Mental Health
Facility Specialization: Certified Community Behavioral Health Clinic
Facility Operation: Private non-profit organization
Licence / Certification / Acreditation: Federally Qualified Health Center
Age Groups Accepted: Children/Adolescents
Facility Details
Type of Care
- Substance use treatment
- Mental health treatment
- Treatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Payment & Insurance Accepted
- Community Mental Health Block Grants
- Medicare
- Medicaid
- Private health insurance
- State-financed health insurance plan other than Medicaid
- State mental health agency (or equivalent) funds
- State welfare or child and family services funds
Payment Assistance Available
- Payment assistance (check with facility for details)
- Sliding fee scale (fee is based on income and other factors)
Facility Services
Treatment & Recovery
- Housing services
- Mentoring/peer support
Assessment / Pre-Treatment
- Screening for tobacco use
Special Programs / Groups Offered
- Young adults
- Criminal justice (other than DUI/DWI)/Forensic clients
- Clients with co-occurring mental and substance use disorders
- Clients who have experienced trauma
- Persons experiencing first-episode psychosis
- Persons with post-traumatic stress disorder (PTSD)
- Children/adolescents with serious emotional disturbance (SED)
- Persons 18 and older with serious mental illness (SMI)
Emergency Health Services
- Crisis intervention team
- Psychiatric emergency onsite services
- Psychiatric emergency walk-in services
Education and Counseling Services
- Smoking/vaping/tobacco cessation counseling
Additional Services
Language Services
- Sign language services for the deaf and hard of hearing
Additional Services
- Assertive community treatment
- Court-ordered outpatient treatment
- Family psychoeducation
- Intensive case management
- Illness management and recovery
- Psychosocial rehabilitation services
- Vocational rehabilitation services
- Case management service
- Integrated primary care services
- Suicide prevention services
- Education services
Smoking & Vaping Policy
- Smoking not permitted
- Vaping not permitted
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