Lipoxide (Chlordiazepoxide)


What is Lipoxide Used to Treat?

Lipoxide® is the brand name for the drug Chlordiazepoxide. It is used to treat anxiety, particularly prior to surgery. Lipoxide is also used to treat alcohol withdrawal and psychosis caused by severe alcohol withdrawal.

How is Lipoxide Used?

Lipoxide is an oral medication that acts in the central nervous system and increases the effects GABA. It produces a calming effect which relieves anxiety.

What are the Side Effects of Lipoxide?

Lipoxide may cause side effects, some of which may be serious. Patients taking Lipoxide should consult their health care provider immediately if they experience any of the following side effects:

  • Nausea/vomiting
  • Constipation/diarrhea
  • Dizziness
  • Blurred vision
  • Headache
  • Change in sex drive
  • Sleep disturbances
  • Tremor/uncontrolled movements/twitching
  • Problems with urination/dark colored urine
  • Mental status or mood changes
  • Stomach or abdominal pain
  • Fainting
  • Fatigue
  • Fever
  • Sore throat
  • Trouble breathing
  • Rash
  • Jaundice

It is possible to experience side effects not listed here and any issues or problems with Lipoxide should be discussed with a health care provider.


As with any medication patients should take necessary precautions. With Lipoxide it is important to be aware of the following:

  • Do not drive, use machinery or engage in any behavior that requires alertness as the side associated with Lipoxide may increase risk of injury.
  • Do not drink alcohol while taking Lipoxide.
  • Persons with a history of liver or kidney disease may not be candidates for Lipoxide use.
  • Persons with COPD, sleep apnea, lung, breathing problems or blood disorders may not be candidates for Lipoxide use.
  • Elderly persons who take Lipoxide may be more prone to side effects, especially fatigue.
  • Do not take Lipoxide if you are pregnant, considering pregnancy or nursing.
  • Do not suddenly discontinue use or change dosage without checking with your health care provider.
  • Lipoxide may have negative interactions with other medication particularly sodium oxybate. Some over the counter medications that cause drowsiness may have increased side effects with taken with Lipoxide therefore, it is important to fully disclose all medications including over the counter medicines to your health care provider before taking Lipoxide. Further, smoking may decrease the effectiveness of Lipoxide necessitating a change in dosage.
  • Lipoxide may also affect results of some lab tests and blood work. Be sure to tell your lab tech and doctor you are taking Lipoxide.
  • For any questions regarding the use of Lipoxide and to help determine if it is the best medication for you, consult your health care provider.




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