Zoloft (Sertraline) is used in the treatment of all types of depression. It may also be used to panic disorder, panic attacks, social phobia, obesity, or obsessive-compulsive disorder (OCD), and post-traumatic stress disorder (PTSD). Zoloft (Sertraline) works by helping to restore the balance of certain natural chemicals in the brain.

Zoloft (Sertraline) has also been used to treat a severe form of premenstrual syndrome (premenstrual dysphoric disorder- PMDD) and a sexual function problem in men (premature ejaculation).

Take Zoloft (Sertraline) by mouth usually once daily with or without food; or as directed by your doctor. It is recommended that you take your dosage at the same time each day, either in the morning or in the evening. The dosage is based on your medical condition and response to therapy. It is important to continue taking this medication as prescribed even if you feel well.


50 mg, 100 mg.

Dosages: Actual dosage must be determined by a physician.

Start: 50 mg 3 times daily.
Increases: 50 mg in 3 or 4 day intervals.
Maximum: 400 mg in 24 hours.

Normal dosage:

If under 12 years of age, DO NOT USE.
12 to 60 years of age, 50 mg.
Over 60 years of age, Lower dosage increased cautiously.

Problems with:

Liver Function: Lower dosage, as needed. In rare cases,may cause liver damage.
Kidney Function: N/A.

Take With: With or without food.

Full Benefits In: 1 to 4 weeks.

Missed Dose(s): If within one hour take, if over an hour skip and then continue on your normal schedule. Never Take a Double Dose.

Stop Taking If: Do not stop without consulting your physician.

Symptoms of overdose may include: irregular heartbeat, fainting, severe dizziness or lightheadedness. If overdose is suspected, contact your local poison control center or emergency room immediately.


Tell your doctor your medical history, especially of: liver problems, kidney disease, seizures, heart problems, and allergies. This drug may make you dizzy or drowsy; use caution engaging in activities requiring alertness such as driving or using machinery. Limit alcoholic beverages. Caution is advised when using this product in the elderly because they may be more sensitive to the effects of the drug. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. This drug passes into breast milk. Because of the potential risk to the infant, breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding.

The habit-forming potential is none.

Do not take this drug if you have taken a MAO inhibitor,monoamine oxidase ( MAO ) in the last five weeks.

Do not take this drug if you plan to have electroconvulsive therapy ( ECT ).

Do not take this drug if you are pregnant, try some non-drug alternatives.

Do not take this drug if planning to become pregnant. Do not take if you are breast-feeding.

Do not give this drug to any one under eighteen. If over sixty only use drug in small doses and with close monitoring of Zoloft side effects.

Do not use if: You had negative reactions to this drug in the past.

Inform your Doctor if:

  • you had negative reactions to this drug in the past.
  • if you have a history of seizures, recent heart attack, kidney disease, Parkinson's disease, or liver disease.
  • if you are taking any other prescription or nonprescription drug.
  • if you plan to be under anesthesia or having any surgery in the next few months,also if you will be undergoing any medical tests.

Zoloft Side Effects and Symptoms

Common: Diarrhea, dizziness, drowsiness, dry month, headache, indigestion, fatigue, insomnia,nausea, nervousness, tingling, or vomiting.

Rare: Altered taste, abnormal vision, chest pain, confusion, hallucinations, headache, hives,impaired concentration, increased blood pressure, numbness,paresthesias, or tongue ulceration.

See physician always: Altered taste, abnormal vision, chest pain,confusion, dry month, hallucinations, impaired concentration, increased blood pressure, numbness, paresthesias, or tongue ulceration.

See physician if severe: Diarrhea, dizziness, drowsiness, indigestion, fatigue, insomnia, nausea, nervousness, tingling, or vomiting.

Stop taking and see physician NOW: Anemia, hives, skin rash, or seizures.


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