Pimozide ( Orap ) data sheet

Pimozide ( Orap ) is an antipsychotic drug of high-potency. Used in the treatment of psychotic thinking and hallucinations. Pimozide ( Orap ) is not the drug of first choice, because of some serious risk. Given only to people that do not responded to other medicines.


Antacids containing aluminum or magnesium should not be taken one hour before taking this drug and never right after.

Only take this drug and Heterocyclic antidepressants with careful monitoring. Also check with your physician if you are taking central nervous system depressants like antihistamines, hay fever medicines, sedatives, narcotics, anesthetics, barbiturates or muscle relaxants. Also check with your physician if you are taking a vasodilator (drug that dilate blood vessels.)

If you smoke blood levels of this drug need to be taken. Smoking drops this drugs level in the blood.

The habit-forming potential is none, but long term use may lead to Tardive Dyskinesia or to Neuroleptic Malignant syndrome.

Do not take this drug if you are pregnant ( Only take if the mother's or baby's life is endangered ).

Do not take this drug if planning to become pregnant. Do not take if you are breast-feeding.

Do not give this drug to anyone under twelve. Only use drug in small doses at first if over sixty and with close monitoring. Also if over sixty be careful when standing up because blood pressure may be lowered enough to impair balance.

Do not use if: You had negative reactions to this drug in the past.

Inform your Doctor if:

  • you had negative reactions to this drug in the past.
  • if you have liver, kidney or heart disease.
  • if you have epilepsy or asthma.
  • if you are taking any other prescription or nonprescription drug.
  • if you plan to be under anesthesia or having any surgery in the next few months, also if you will be undergoing any medical tests.
  • if you are on a special diet ( low-salt / low-sugar or any other ).

Pimozide ( Symptoms or Effects )

Common: Sedation, high or low blood pressure, sore breast / milk secretion, vision problems, constipation, dry mouth or dizziness / light headed.

Rare: Difficulty speaking, difficulty swallowing, trembling / shaking, coordination problems, muscle spasms, skin rash, diarrhea, headache, change of appetite, nausea / vomiting, swelling / puffiness in face, seizures, fever, muscle stiffness, restlessness, sexual problems or reduced urinary output.

See physician always: Difficulty speaking, difficulty swallowing, trembling / shaking, high or low blood pressure, muscle spasms, skin rash, swelling / puffiness in face, seizures, fever, muscle stiffness, restlessness, sexual problems, reduced urinary output or or sore breast / milk secretion.

See physician if severe: Coordination problems, vision problems, constipation, dry mouth, dizziness / light headed, sedation, diarrhea, headache, change of appetite or nausea / vomiting.

See physician NOW: Reduced urinary output, fever, skin rash or swelling / puffiness in face.

Stop taking and see physician NOW: Seizures, Difficulty speaking or difficulty swallowing.


The information provided on the PsyWeb.com is designed to support, not replace, the relationship that exists between a patient/site visitor and his/her health professional. This information is solely for informational and educational purposes. The publication of this information does not constitute the practice of medicine, and this information does not replace the advice of your physician or other health care provider. Neither the owners or employees of PsyWeb.com nor the author(s) of site content take responsibility for any possible consequences from any treatment, procedure, exercise, dietary modification, action or application of medication which results from reading this site. Always speak with your primary health care provider before engaging in any form of self treatment. Please see our Legal Statement for further information.

PsyWeb Poll

Are you currently taking or have you ever been prescribed anti-depressants?
Total votes: 3979