Supplies blood to most of the medial surface of the cerebral cortex ( anterior three fourths ), frontal pole ( via cortical branches ), and anterior portions of the corpus callosum.

Perforating branches ( including the recurrent artery of Heubner and Medial Lenticulostriate Arteries ) supply the anterior limb of the internal capsule, the inferior portions of head of the caudate and anterior globus pallidus.

Blockage Affects:

Bilateral occlusion of Anterior Cerebral Arteries at their stems results in infarction of the anteromedial surface of the cerebral hemispheres:

• Paraplegia affecting lower extremities and sparing face/hands.
• Incontinence.
• Abulic and motor aphasia.
• Frontal lobe Symptoms: personality change, contralateral grasp reflex.

Unilateral occlusion (distal to Ant. Comm. origin) of Anterior Cerebral Artery produces contralateral sensorimotor deficits mainly involving the lower extremity with sparing of face and hands.